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Using the case records of Mayo Clinic patients,121 patients with a diagnosis of benign fasciculations were identified.All had a normal neurologic examination and normal electrophysiological studies,except for fasciculation potentials.Interviews by telephone were conducted 2 to 32 years after diagnosis.None of the patients developed symptomatic motor neuron disease.Forty individuals were in health care careers.A subset of 19 patients described acute onset of fasciculations following a viral infection.Benign fasciculations are not a prelude to progressive motor neuron disease. |
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